Milkshake

Food buffs come in tiers, and this one lands on the top rung, the same level you would otherwise reach only by standing at a cooking pot with the right ingredients. It drops ready to eat, which is the whole appeal: the strongest food effect in the game with no station, no recipe and no gathering trip attached.

The tortoises and mermen that carry it live in the ice caves, and you have reason to be down there through most of early Hardmode anyway. Take it when it shows up rather than grinding for it. One buff runs long enough to cover a full boss session, so a handful lasts a long time.

The tooltip is lifted from the Kelis single of the same name, which is why it reads as a taunt instead of a description of a drink.